hrp0094p2-187 | Fat, metabolism and obesity | ESPE2021

Effect of Semaglutide on body weight in obese children with craniopharyngioma: a preliminary report

Jourdren Marie , Coutant Regis , Bouhours Nouet Natacha , Amsellem Jager Jessica , Donzeau Aurelie , Levaillant Lucie , Delion Mathieu ,

Background: Pituitary insufficiency and severe obesity are common sequelae of craniopharyngioma and its treatment. Once weekly glucagon-like Peptide 1 (GLP1) analog’s semaglutide has recently shown efficacy in adults with common obesity.Objective: We evaluated the efficacy and safety of Semaglutide, a once-weekly GLP-1 analog, in 6 children with craniopharyngioma and morbid obesity.Subjects an...